Unaskable questions

At a party this week I witnessed the following exchange between two friends who hadn't seen each other in a long time, one of whom has ongoing medical problems.

Asker: How are you doing, dear?
Answerer: I'm . . . okay.
Asker: Now, are you really okay, or are you just saying that?
Answerer: (bursts into tears)
Asker: (hugging her) There, there.
Me: (not out loud) What were you thinking?  She obviously didn't want to talk about it!  Did you provoke her to that just so you could comfort her?

There is a category of question that only has one acceptable answer.  They include, "Do I look fat in this?" and "Do you love me?" and "Do you regret marrying him?"   If there's only one answer you can accept hearing, or there's only one answer the other can acceptably give, don't ask.